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出版商:John Wiley & Sons
语言:英语
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书籍目录

书籍简介

本书pdf是 文字版

Introduction

Ion Sources

1.1 Electron Ionization

1.2 Chemical Ionization

1.3 Field Ionization

1.4 Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry

1.5 Field Desorption

1.6 Plasma Desorption

1.7 Laser Desorption

1.8 Matrix-Assisted Laser Desorption Ionization

1.9 Thermospray

1.10 Atmospheric Pressure Ionization

1.11 Electrospray

1.12 Atmospheric Pressure Chemical Ionization

1.13 Atmospheric Pressure Photoionization

1.14 Atmospheric Pressure Secondary Ion Mass Spectrometry

1.15 Inorganic Ionization Sources

1.16 Gas-Phase Ion-Molecule Reactions

1.17 Formation and Fragmentation of Ions: Basic Rules

Mass Analysers

2.1 Quadrupole Analysers

2.2 Ion Trap Analysers

2.3 The Electrostatic Trap or ‘Orbitrap’

2.4 Time-of-Flight Analysers

2.5 Magnetic and Electromagnetic Analysers

2.6 Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry

2.7 Hybrid Instruments

Detectors and Computers

3.1 Detectors

3.2 Computers

Tandem Mass Spectrometry

4.1 Tandem Mass Spectrometry in Space or in Time

4.2 Tandem Mass Spectrometry Scan Modes

4.3 Collision-Activated Decomposition or Collision-Induced Dissociation

4.4 Other Methods of Ion Activation

4.5 Reactions Studied in MS/MS

4.6 Tandem Mass Spectrometry Applications

Mass Spectrometry/Chromatography Coupling

5.1 Elution Chromatography Coupling Techniques

5.2 Chromatography Data Acquisition Modes

5.3 Data Recording and Treatment

Analytical Information

6.1 Mass Spectrometry Spectral Collections

6.2 High Resolution

6.3 Isotopic Abundances

6.4 Low-mass Fragments and Lost Neutrals

6.5 Number of Rings or Unsaturations

6.6 Mass and Electron Parities, Closed-shell Ions and Open-shell Ions

6.7 Quantitative Data

Fragmentation Reactions

7.1 Electron Ionization and Fragmentation Rates

7.2 Quasi-Equilibrium and RRKM Theory

7.3 Ionization and Appearance Energies

7.4 Fragmentation Reactions of Positive Ions

7.5 Fragmentation Reactions of Negative Ions

7.6 Charge Remote Fragmentation

7.7 Spectrum Interpretation

Analysis of Biomolecules

8.1 Biomolecules and Mass Spectrometry

8.2 Proteins and Peptides

8.3 Oligonucleotides

8.4 Oligosaccharides

8.5 Lipids

8.6 Metabolomics

Exercises

Appendices

1 Nomenclature

2 Acronyms and abbreviations

3 Fundamental Physical Constants

4A Table of Isotopes in Ascending Mass Order

4B Table of Isotopes in Alphabetical Order

5 Isotopic Abundances (in %) for Various Elemental Compositions CHON

6 Gas-Phase Ion Thermochemical Data of Molecules

7 Gas-Phase Ion Thermochemical Data of Radicals

8 Literature on Mass Spectrometry

9 Mass Spectrometry on Internet